Studies on transcobalamin (TC). 1. Detection of TC II isoproteins in human serum

Studies on transcobalamin (TC). 1. Detection of TC II isoproteins in human serum.

Transport of therapeutic cyanocobalamin in the congenital deficiency of transcobalamin II (TC II).

Cobalamin (Cbl) transport was studied in the circulation of a child deficient in transcobalamin II (TC II) after 1.0 mg of cyanocobalamin (CN-Cbl) either intramuscularly or orally. Pertinent observations include the following: (1) There was no detectable TC II in the serum as measured immunologically or by binding capacities in vivo or in vitro. (2) Transcobalamin I (TC I) was present in at lea...

Comparison of Tc-99m Ethylenedicysteine (Tc-99m EC) with Tc-99m DPTA in evaluation of renal disease [Persian]

Tc-99m-EC is a new renal radiopharmaceutical introduced as an alternative for Tc-99m MAG3. Twenty-three normal volunteers and patients in different .stages of renal disease were evaluated with Te-99m EC and Tc-99m DTPA. The mean initial uptake of EC was significantly higher as compared to DTPA. There was a high correlation between rectangular and hand-drawn ROls for kidney and background,...

Functional human transcobalamin II isoproteins are secreted by insect cells using the baculovirus expression system.

Transcobalamin II (TCII) is a cobalamin (Cbl, vitamin B12)-binding protein in mammalian plasma that facilitates the cellular uptake of the vitamin. To obtain human TCII in sufficient quantity for analytical studies, the complementary DNA (cDNA) encoding TCII was inserted into the plasmid PVL 1393, and the baculovirus expressing TCII was obtained by homologous recombination in Spodoptera frugipe...

Anelastic spectroscopy studies of high-Tc superconductors

Two families of cuprates exhibiting high-Tc superconductivity, YBa2Cu3O6+x (YBCO) and La2xSrxCuO4+δ (LSCO), have been extensively studied by anelastic spectroscopy, by measuring the complex dynamic Young’s modulus E (ω, T ) = E′ + iE′′ of ceramic samples at frequencies of 0.5-20 kHz between 1 and 900 K. Results are also presented on oxygen vacancies in the ruthenocuprate RuSr2GdCu2O8−δ. The ela...